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Graph Drawing and Analysis for Biomedical Applications



In modern biology, microarray technology is used in large-scale experiments to collect data of thousands of genes and proteins in parallel. Together with their mutual interactions these genes and proteins form genetic networks, which are studied with methods from bioinformatics in order to understand gene and protein functions.

Mathematically, genetic networks are represented by directed graphs. The aim of this project is the development of an extensible framework for the visualization and analysis of genetic networks. Bioinformatics researchers shall be able to add new analysis algorithms to the framework via a Java-based plugin mechanism. The visualization of complex genetic networks shall be possible in 2D as well as in 3D in a virtual reality environment.

The master project is part of a two-year research project on Biomedical Graph Analysis, which is funded with travel grants by the German Academic Exchange Service (DAAD).


- Java 6, Eclipse framework, OSGi service platform
- Virtual reality laboratory, OpenGL rendering API
- Graph drawing and analysis algorithms

Project Details
- Collaboration with King‘s College London (UK), School of Medicine, Dept. of Medical and Molecular Genetics
- Participants: 6 students, 2 professors
- Duration: 2007-09 to 2008-02

Art des Projektes: Master Project - Specialization Graphics and Visualization

Zeitraum: WS 07/08-SS08

Projektstand: begonnenes Projekt

Projektdauer: 1 Semester

Projektart: Projekt im Hauptstudium

Projektleitung: Prof. Dr. Frauke Sprengel ( IV / Angewandte Informatik (MIN) )

Prof. Dr. Volker Ahlers ( IV / Angewandte Informatik (MIN) )

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